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2011 University of Southern Mississippi Schedule/Results
| Date | Opponent | Location | TV | Outcome/Time |
| Fri., Aug. 26 | Southern Miss 3, Chattanooga 0 | Hattiesburg, Miss. | | |
| Sat., Aug. 27 | Southern Miss 3, Northwestern State 1 | Hattiesburg, Miss. | | Gametracker |
| | Southern Miss 3, Jackson State 0 | Hattiesburg, Miss. | | Gametracker |
| Fri., Sep. 2 | Iowa State 3, Southern Miss 0 | Ames, Iowa | | |
| | Iowa 3, Southern Miss 1 | Ames, Iowa | | |
| Sat., Sep. 3 | Arizona State 3, Southern Miss 1 | Ames, Iowa | | |
| Fri., Sep. 9 | Milwaukee 3, Southern Miss 1 | Milwaukee, Wisc. | | Gametracker |
| | Marquette 3, Southern Miss 0 | Al McGuire Center | | Gametracker |
| Sat., Sep. 10 | Southern Miss 3, Akron 2 | Milwaukee, Wisc. | | Gametracker |
| Fri., Sep. 16 | Houston Baptist 3, Southern Miss 1 | Houston, Texas | | |
| | Southern Miss 3, Louisiana Tech 0 | Houston, Texas | | |
| Sat., Sep. 17 | Southern Miss 3, Southeastern Louisiana 0 | Houston, Texas | | |
| Fri., Sep. 23 | Houston 3, Southern Miss 2 | Houston, Texas | | Gametracker |
| Sun., Sep. 25 | Rice 3, Southern Miss 2 | Houston, Texas | | Gametracker |
| Fri., Sep. 30 | Southern Miss 3, Memphis 0 | Hattiesburg, Miss. | | Gametracker |
| Sun., Oct. 2 | UAB 3, Southern Miss 1 | Hattiesburg, Miss. | | Gametracker |
| Sat., Oct. 8 | Tulsa 3, Southern Miss 0 | Tulsa, Oklahoma | | Gametracker |
| Sun., Oct. 9 | Tulsa 3, Southern Miss 0 | Tulsa, Oklahoma | | Gametracker |
| Fri., Oct. 14 | Southern Miss 3, East Carolina 0 | Hattiesburg, Miss. | | Gametracker |
| Sun., Oct. 16 | Southern Miss 3, Marshall 0 | Hattiesburg, Miss. | | Gametracker |
| Wed., Oct. 19 | Tulane 3, Southern Miss 0 | New Orleans, La. | | Gametracker |
| Fri., Oct. 21 | Southern Miss 3, UTEP 0 | Memorial Gym | | |
| Sun., Oct. 23 | Southern Miss 3, UCF 2 | Hattiesburg, Miss. | | Gametracker |
| Fri., Oct. 28 | Marshall 3, Southern Miss 1 | Huntington, W. Va. | | Gametracker |
| Sun., Oct. 30 | Southern Miss 3, East Carolina 0 | Greenville, N.C. | | |
| Fri., Nov. 4 | Southern Miss 3, SMU 2 | Reed Green Coliseum | | |
| Sat., Nov. 5 | SMU 3, Southern Miss 2 | Reed Green Coliseum | | Gametracker |
| Fri., Nov. 11 | Southern Miss 3, UAB 0 | Birmingham, Ala. | | |
| Sat., Nov. 12 | Southern Miss 3, Memphis 1 | Memphis, Tenn. | | Gametracker |
| Fri., Nov. 18 | Rice 3, Southern Miss 2 | Hattiesburg, Miss. | | Gametracker |
| Sun., Nov. 20 | Southern Miss 3, Houston 1 | Hattiesburg, Miss. | | Gametracker |
| Tue., Nov. 22 | Southern Miss 3, Tulane 0 | Reed Green Coliseum | | Gametracker |
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Who will win this week's C-USA Baseball Championship?
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